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Consolidative Thoracic Radiotherapy Displays Safety, Efficacy in ES-SCLC
No treatment-related deaths were observed with radiotherapy for extensive-stage small cell lung cancer, and most adverse effects were grade 1 or 2.
Dordaviprone Presents Therapeutic Option for Diffuse Midline Glioma Type
Historical standards for H3 K27M-mutant diffuse midline glioma treatment may harm healthy central nervous system cells, according to Ashley L. Sumrall...
Low Dose-Averaged LET Exhibits Poor Local Control in Pancreatic Cancer
The retrospective study is the largest to evaluate the relationship between dose-averaged LET profiles and local control after CIRT for pancreatic can...
Chemoradiation May Convert Unresectable Pancreatic Cancers for Resection
Induction chemotherapy may allow investigators to biologically select patients with a favorable prognosis who benefit most from chemoradiotherapy.
Teclistamab Real-World Data and Trial Results Show Promise in R/R Multiple Myeloma
Experts discussed teclistamab's efficacy in multiple myeloma, highlighting real-world data and treatment protocols.
Carfilzomib Regimens Improve MRD Outcomes in Older, Fit NDMM Population
Phase 3 findings may contribute to the selection of triplet or quadruplet therapies in newly diagnosed multiple myeloma via frailty-based assessments.
Tuspetinib Exhibits Enhanced Efficacy in Diverse Newly Diagnosed AML Group
No minimal residual disease-negativity was observed with tuspetinib in patients with AML, including in a patient with more than 7 months of follow-up...
Further Research on Anti-CD38 mAbs Warranted in Multiple Myeloma
A systematic review of 8 randomized trials showed that anti-CD38 monoclonal antibodies did not improve overall survival in high-risk subgroups.
Newly Approved Agent for Diffuse Midline Glioma Shows Tolerable AE Profile
Dordaviprone was recommended at a dose of 625 mg orally once weekly for adults, and the recommended dosage is based on body weight for pediatric patie...
Emotional Distress May Confer Worse Immunotherapy Outcomes in NSCLC
Prior data from the STRESS-LUNG-1 trial introduced emotional distress as a “psycho-biomarker” for immunotherapy efficacy in non–small cell lung cancer...
Consolidative Thoracic Radiotherapy Displays Safety, Efficacy in ES-SCLC
Dordaviprone Presents Therapeutic Option for Diffuse Midline Glioma Type
Low Dose-Averaged LET Exhibits Poor Local Control in Pancreatic Cancer
Chemoradiation May Convert Unresectable Pancreatic Cancers for Resection
Teclistamab Real-World Data and Trial Results Show Promise in R/R Multiple Myeloma
Carfilzomib Regimens Improve MRD Outcomes in Older, Fit NDMM Population
Tuspetinib Exhibits Enhanced Efficacy in Diverse Newly Diagnosed AML Group
Further Research on Anti-CD38 mAbs Warranted in Multiple Myeloma
Newly Approved Agent for Diffuse Midline Glioma Shows Tolerable AE Profile
Emotional Distress May Confer Worse Immunotherapy Outcomes in NSCLC
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