Gastroenterology

Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD Huang W, Zhang Y, Das N, et al. Fibroblast lipid meta...

IMMUNOLOGY AUTOIMMUNE DISEASE PANCREATIC ANTIBODIES PANCREATITIS ALLERGY KEY MESSAGES IgG4 antibodies exhibit unique structural and functional propert...

LIVER METABOLISM GENE THERAPY DRUG DEVELOPMENT Key messages RNA-based drugs are emerging as one of the most promising therapeutic strategies, able to...

Introduction Alcohol-related liver diseases (ALDs) encompass a spectrum of pathophysiological states, from early steatosis to cirrhosis and hepatocell...

Introduction In early 2022, a strong increase in cases of acute hepatitis of unknown origin (AHUO) among children was noted, particularly in the UK.1–...

Introduction Human serum albumin (HSA) is the most abundant protein (35–50 g/L) in the human plasma and maintains plasma osmotic pressure.1 Clinically...

Introduction Severe acute pancreatitis (SAP), defined as persistent organ failure (OF >48 hours) or pancreatic infection, is an unpredictable and pote...

Funding This work was supported, in part, by grants from Ministerio de Ciencia, Innovación y Universidades (MCIU, Madrid, Spain) to FXR (PID2021-12812...

Contributors XS and WC designed, edited and led out this study’s experiments. XS performed most of the experiments. HL, CG and XM performed some exper...

Introduction In the years since the original study,1 it has become widely accepted that measurement of faecal haemoglobin concentration (f-Hb) with a...