General Medicine
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Royalty financing deepens exposure to small cell lung cancer revenues
1. Royalty Pharma struck a deal worth up to 950 million dollars to buy into Amgen’s DLL3 directed bispecific for SCLC (small cell lung cancer). 2. The...
Pre-conception computed tomography ionizing radiation may be associated with worse reproductive outcomes
1. In this population-based cohort study, women who had received at least one computer tomography scan prior to conception had higher rates of spontan...
Ending Ryan White services may increase human immunodeficiency virus incidence
1. In this simulation study involving persons with human immunodeficiency virus living in the United States, ending Ryan White services in cities with...
Pancreatic beta-cell secretory products in the diagnosis and risk stratification of gestational diabetes mellitus: a prospective longitudinal cohort study
1. 30- and 60-minute C-peptide levels during an OGTT at 16–18 weeks gestation were significantly elevated in women who later developed GDM, suggesting...
2 Minute Medicine Rewind September 8, 2025
Effectiveness and user experiences of a valgus brace in patients with knee osteoarthritis: A mixed-method randomised controlled trial 1. After six mon...
Leqembi gains at home injection for maintenance dosing
1. The FDA cleared a subcutaneous maintenance version of lecanemab, allowing patients with AD (Alzheimer’s disease) to continue treatment at home. 2....
β-Blocker Use and Health Status Among Patients With Heart Failure With Preserved Ejection Fraction
1. In patients with heart failure with preserved ejection fraction (HFpEF), β-blocker use was not associated with concurrent baseline health status or...
Novo’s self replicating RNA push expands cardiometabolic pipeline
1. Novo Nordisk expanded into self replicating RNA for obesity and T2D (type 2 diabetes), signaling modality diversification beyond peptides. 2. The c...
Computed Tomographic Angiography and Yield for Gastrointestinal Bleeding in the Emergency Department
1. Between the years 2017 and 2023, the proportion of total computed tomographic angiography (CTA) examinations related to gastrointestinal bleeding (...
2 Minute Medicine: Pharma Roundup- Obesity RNA deal, at-home Alzheimer’s dosing, oncology royalty financing, and first Bruton’s Tyrosine Kinase Inhibitor for Immune Thrombocytopenia [September 3, 2025
Novo’s srRNA push expands cardiometabolic pipeline On August 28, Novo Nordisk announced a collaboration with Replicate Bioscience to pursue self repli...
Royalty financing deepens exposure to small cell lung cancer revenues
Pre-conception computed tomography ionizing radiation may be associated with worse reproductive outcomes
Ending Ryan White services may increase human immunodeficiency virus incidence
2 Minute Medicine Rewind September 8, 2025
Leqembi gains at home injection for maintenance dosing
β-Blocker Use and Health Status Among Patients With Heart Failure With Preserved Ejection Fraction
Novo’s self replicating RNA push expands cardiometabolic pipeline
Computed Tomographic Angiography and Yield for Gastrointestinal Bleeding in the Emergency Department
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