Oncology
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Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk
Figure 1 shows the study design [14]. Firstly, we estimated the effect of BMI and WHR on 856 plasma metabolites using MR. Secondly, we estimated the e...
Lipidomic profiling of human bile distinguishes cholangiocarcinoma from benign bile duct diseases with high specificity and sensitivity: a prospective descriptive study
Study design This was a single-centre, prospective descriptive study of bile samples collected by ERCP from patients with CCA or benign disease. All p...
Anti-PD-1 treatment response is associated with the influx of circulating myeloid and T-cell subsets into the metastatic melanoma tumor microenvironment
Study population and clinical data collection This study retrospectively included 15 advanced-stage non-uveal melanoma patients (stage IV) who receive...
m1A methylase TRMT6 promotes neuroblastoma development by demethylating SST mRNA in an m1A/YTHDF2-dependent manner
Maris JM, Hogarty MD, Bagatell R, Cohn SL. Neuroblastoma. Lancet. 2007;369:2106–20. Smith EI, Haase GM, Seeger RC, Brodeur GM. A surgical perspective...
Correction: Wnt/ERK/CDK4/6 activation in the partial EMT state coordinates mammary cancer stemness with self-renewal and inhibition of differentiation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribut...
Managing Dose Reductions With TAS-102 Therapy in Colorectal Cancer
During a conversation with CancerNetwork®, Nicholas James Hornstein, MD, PhD, discussed results from the phase 2 INTERCEPT-TT trial (NCT05343013) that...
Outpatient Dosing of Teclistamab: Lessons From TecPIONEER 2.0
Outpatient step-up dosing of bispecific antibody therapy in multiple myeloma has been shown to be feasible in several academic centers and recent clin...
Man Up? The Truth About Men's Health After Cancer
In a recent episode of the Oncology-on-the-Go podcast in collaboration with the American Psychosocial Oncology Society (APOS), host Daniel C. McFarlan...
TAS-102 Achieves ctDNA Clearance, Improves DFS in Colorectal Cancer
In the phase 2 INTERCEPT-TT trial (NCT05343013), TAS-102 demonstrated improved levels of circulating tumor DNA (ctDNA) clearance vs a synthetic contro...
KIM-1, Blood-Based Biomarkers May Show Promise in Kidney Cancer
As part of a collaboration between CancerNetwork® and KidneyCAN, Michael B. Atkins, MD, spoke about novel biomarkers that may play a role in the detec...
Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk
Managing Dose Reductions With TAS-102 Therapy in Colorectal Cancer
Outpatient Dosing of Teclistamab: Lessons From TecPIONEER 2.0
Man Up? The Truth About Men's Health After Cancer
TAS-102 Achieves ctDNA Clearance, Improves DFS in Colorectal Cancer
KIM-1, Blood-Based Biomarkers May Show Promise in Kidney Cancer
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