Oncology
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Dato-DXd Increases Intracranial Responses/PFS in NSCLC With Brain Mets
Results from a post-hoc analysis of the phase 3 TROPION-Lung01 trial (NCT04656652) shared at the International Association for the Study of Lung Cance...
DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps
Chen et al. demonstrate that DNASE1L3+ dendritic cells degrade neutrophil extracellular traps, thereby facilitating CD8+ T cell infiltration, effector...
When human cancer goes neural
Invasion along nerves is prognostically detrimental in pancreatic and other cancers, yet its microenvironmental composition in humans remains poorly u...
Dendritic cells function beyond antigen presentation
In this issue of Cancer Cell, Chen et al. identify DNASE1L3-expressing dendritic cells (DCs) as enhancers of anti-tumor immunity. By degrading neutrop...
Engineering myeloid cells for cancer immunotherapy
Macrophages naturally infiltrate tumors, modulate tumor microenvironment, phagocytose tumor cells, and present antigens to induce T cell responses. Th...
Cardiovascular Considerations in Breast Cancer Treatment and Survivorship
In this episode, CancerNetwork® spoke with Joseph S. Wallins, MD, MPH, cardiology fellow at Weill Cornell Medicine, about a review of cardiotoxicities...
What’s Next for Bispecifics: Earlier Use and More
Bispecific antibodies in multiple myeloma are currently approved for patients who have undergone at least 4 prior lines of therapy, but their use is r...
Clinical Trial Review: KEYNOTE-426
Video content above is prompted by the following: Pembrolizumab plus axitinib emerged as the first FDA-approved IO-TKI combination for first-line clea...
Clinical Trial Review: CheckMate 9ER
Video content above is prompted by the following: CheckMate 9ER established nivolumab plus cabozantinib as a potent immunotherapy-tyrosine kinase inhi...
Reducing Animal Proteins, Increasing Fiber May Benefit Patients With Cancer
In an interview with CancerNetwork® on nutrition in cancer treatment, Denise B. Reynolds, registered dietitian at Atrium Health Levine Cancer, discuss...
Dato-DXd Increases Intracranial Responses/PFS in NSCLC With Brain Mets
When human cancer goes neural
Dendritic cells function beyond antigen presentation
Engineering myeloid cells for cancer immunotherapy
Cardiovascular Considerations in Breast Cancer Treatment and Survivorship
What’s Next for Bispecifics: Earlier Use and More
Clinical Trial Review: KEYNOTE-426
Clinical Trial Review: CheckMate 9ER
Reducing Animal Proteins, Increasing Fiber May Benefit Patients With Cancer
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