EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated with a significant reduction in the composite outcome of cardiovascular death, stroke, and hospitalization for worsening heart failure or acute coronary syndrome compared to usual care in patients with newly diagnosed atrial fibrillation (AF). Original Date […]
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