NeurologyLive® Friday 5 — September 12, 2025
Advertisement News|Articles|September 12, 2025 NeurologyLive® Friday 5 — September 12, 2025 Author(s)Isabella Ciccone, MPH Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending September 12, 2025. Advertisement Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive's widespread coverage in neurology, ranging from newsworthy study findings and FDA action to expert interviews and peer-to-peer panel discussions. 1: FDA Action Update, August 2025: Approvals and Complete Response LetterCatch up on any of the neurology news headlines you may have missed over the course of August 2025, compiled all into 1 place by the NeurologyLive® team.2: Improving Brain Health Through Lifestyle Changes in Older Adults at Risk for Dementia: Rebecca M. Edelmayer, PhDThe vice president of scientific engagement at the Alzheimer's Association shared data presented at AAIC 2025 from the phase 3 U.S. POINTER study among patients at risk for dementia. [WATCH TIME: 4 minutes]3: 2025 LGS Meeting Reflections and Engagement Opportunities in ResearchIn this latest roundtable episode, experts noted that the Lennox-Gastaut syndrome Foundation is a welcoming platform for collaboration, research advancement, and career development in the field. [WATCH TIME: 3 minutes]4: NeuroVoices: Marcus Yountz, on the Promise and Phase 2 Data of Orexin Agent AlixorextonIn our latest NeuroVoices Q&A, Marcus Yountz, VP of clinical development at Alkermes detailed phase 2 results for alixorexton, an oral, selective orexin 2 receptor agonist, in narcolepsy type 1, including benefits for fatigue, cognition, and weakness.5: Eligibility and Safety Considerations for Antiamyloid Alzheimer TherapiesIn this latest Special Report episode, Sharon Cohen, MD, FRCPC, talked about key differences between lecanemab and donanemab in terms of eligibility requirements to the receive the treatment. Supported by Eli Lilly. NewsletterKeep your finger on the pulse of neurology—subscribe to NeurologyLive for expert interviews, new data, and breakthrough treatment updates.Subscribe Now! Advertisement Related ArticlesShared Decision-Making and Ethics in Complex Neurology Clinical Research: Paul Ford, PhDSeptember 12th 2025FDA Hands Complete Response Letter to SL1009 for Pyruvate Dehydrogenase Complex DeficiencySeptember 12th 2025Expanding the Alzheimer Drug Development Pipeline September 12th 2025Special Episode: Understanding Fremanezumab's Expanded Indication in Pediatric MigraineSeptember 12th 2025Enhancing Gene Therapy Safety for Duchenne Through New Recommendations: Barry Byrne, MD, PhDSeptember 11th 2025Shifting Roles in Neurology Education: Insights From the 2025 AUPN Annual MeetingSeptember 11th 2025 Latest CMEMultimediaBurst CME™ Part II: The Evolving Treatment Landscape for Huntington DiseaseSamuel A. 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Zingariello, DOView moreVideoCases and Conversations™: Navigating the Complexities of Managing Myasthenia Gravis in Pediatric and Pregnant Patient PopulationsJohn Brandsema, MD; Neelam Goyal, MDView moreVideoA Breath of Strength: Managing Cancer Associated LEMS and Lung Cancer as OneEstelamari Rodriguez, MD, MPH; Millie Das, MD; Ruham Nasany, MDView moreVideoStriking the Right Nerve: Managing Cancer Associated LEMS in Lung Cancer PatientsAnne Chiang, MD, PhD; J. Douglas Miles, MD, PhD, FAAN; Suma Satti, MDView moreVideoPatient, Provider, and Caregiver Connection: Improving Diagnosis and Care for Adolescent Myasthenia Gravis Patients – A New FrontierAbigail N. Schwaede, MD; Emmanuelle (Noelle) Tiongson, MDView moreVideoA New Era in NMOSD Treatment: Optimizing Therapeutic Transitions and Reducing Patient BurdenShamik Bhattacharyya, MD, MS, FAAN; Mirla Avila, MD; Dean Wingerchuk, MDView moreAudioPER Podcast™: Maximizing the Multidisciplinary Care Outcomes of Patients with Amyotrophic Lateral Sclerosis (ALS)Richard Bedlack, MD, PhDView moreAudioPER Podcast™: Best Strategies for Approaching the Diagnosis of Amyotrophic Lateral Sclerosis (ALS)Terry Heiman-Patterson, MDView moreVideoPER Postgame™: Updates from ANNA in the Management of IgA NephropathyGerald Bernard Appel, MD; Ellie Kelepouris, MD, FACP, FAHAView moreVideoPatient, Provider, and Caregiver Connection: Turning a New Leaf in Acute Pain Management – How Recent Advancements Impact the Treatment ParadigmJeffrey Gudin, MD; Jeffrey Bettinger, PharmDView morePrevious slideNext slide Advertisement Advertisement Trending on NeurologyLive1Enhancing Gene Therapy Safety for Duchenne Through New Recommendations: Barry Byrne, MD, PhD2Expanding the Alzheimer Drug Development Pipeline 3FDA Hands Complete Response Letter to SL1009 for Pyruvate Dehydrogenase Complex Deficiency4Patient-Reported Study Identifies Common Symptoms and Timing During Migraine Prodrome 5Setting Realistic Expectations for Antiamyloid Therapeutics Advertisement News|Articles|September 12, 2025 NeurologyLive® Friday 5 — September 12, 2025 Author(s)Isabella Ciccone, MPH Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending September 12, 2025. Advertisement Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive's widespread coverage in neurology, ranging from newsworthy study findings and FDA action to expert interviews and peer-to-peer panel discussions. 1: FDA Action Update, August 2025: Approvals and Complete Response LetterCatch up on any of the neurology news headlines you may have missed over the course of August 2025, compiled all into 1 place by the NeurologyLive® team.2: Improving Brain Health Through Lifestyle Changes in Older Adults at Risk for Dementia: Rebecca M. Edelmayer, PhDThe vice president of scientific engagement at the Alzheimer's Association shared data presented at AAIC 2025 from the phase 3 U.S. POINTER study among patients at risk for dementia. [WATCH TIME: 4 minutes]3: 2025 LGS Meeting Reflections and Engagement Opportunities in ResearchIn this latest roundtable episode, experts noted that the Lennox-Gastaut syndrome Foundation is a welcoming platform for collaboration, research advancement, and career development in the field. [WATCH TIME: 3 minutes]4: NeuroVoices: Marcus Yountz, on the Promise and Phase 2 Data of Orexin Agent AlixorextonIn our latest NeuroVoices Q&A, Marcus Yountz, VP of clinical development at Alkermes detailed phase 2 results for alixorexton, an oral, selective orexin 2 receptor agonist, in narcolepsy type 1, including benefits for fatigue, cognition, and weakness.5: Eligibility and Safety Considerations for Antiamyloid Alzheimer TherapiesIn this latest Special Report episode, Sharon Cohen, MD, FRCPC, talked about key differences between lecanemab and donanemab in terms of eligibility requirements to the receive the treatment. Supported by Eli Lilly. NewsletterKeep your finger on the pulse of neurology—subscribe to NeurologyLive for expert interviews, new data, and breakthrough treatment updates.Subscribe Now! Advertisement Related ArticlesShared Decision-Making and Ethics in Complex Neurology Clinical Research: Paul Ford, PhDSeptember 12th 2025FDA Hands Complete Response Letter to SL1009 for Pyruvate Dehydrogenase Complex DeficiencySeptember 12th 2025Expanding the Alzheimer Drug Development Pipeline September 12th 2025Special Episode: Understanding Fremanezumab's Expanded Indication in Pediatric MigraineSeptember 12th 2025Enhancing Gene Therapy Safety for Duchenne Through New Recommendations: Barry Byrne, MD, PhDSeptember 11th 2025Shifting Roles in Neurology Education: Insights From the 2025 AUPN Annual MeetingSeptember 11th 2025 Latest CMEMultimediaBurst CME™ Part II: The Evolving Treatment Landscape for Huntington DiseaseSamuel A. Frank, MDView moreIn-Person + Virtual EventCarolina Neuromuscular Disease SummitSeptember 27, 2025View moreVideoEvolving Perspectives in Alzheimer's Disease: Reaching an Earlier Diagnosis, Understanding Neuroinflammation, and Exploring Therapeutic AdvancesAlireza Atri, MD, PhD; Erik S. Musiek, MD, PhD; Malú Gámez Tansey, PhD View moreCase-based SimulationSimulatEd™ From Discomfort to Relief: Acute Pain Management EssentialsJeff Gudin, MDView moreMultimedia Clinical ShowCase: Developing a Personalized Treatment Plan for a Patient with Huntington’s Disease Associated ChoreaDaniel Claassen, MD, MS; Martha A. Nance, MDView moreIn-Person + Virtual EventPutting the Patient First in Acute Pain Management: The PA’s Guide to Incorporating Cutting-Edge Science into their Treatment StrategiesOctober 9, 2025View moreIn-Person Event4th Women in Neurology ConferenceOctober 24-26, 2025Register now!VideoMedical Crossfire® - Optimizing Management for Patients With Generalized Myasthenia Gravis: Focus on Complement InhibitorsJames F. Howard Jr, MD; Nicholas J. Silvestri, MD, FAAN; Neelam Goyal, MDView moreVideoMedical Crossfire®: Integrating Real-World Data to Improve Outcomes for Patients With Multiple SclerosisCarrie M. Hersh, DO, MSc, FAAN; Anna Shah, MDView moreMultimediaBurst CME™: Optimizing Migraine Management – Addressing Unmet Needs, Individualizing Care for Diverse Populations, and Utilizing CGRP Targeted AgentsJessica Ailani, MD, FAHS, FAAN; Paul G. Mathew, MD, DNBPAS, FAAN, FAHSView moreMultimediaBurst CME™: Setting the Stage – Individualizing Migraine Care for Diverse Populations Across Care SettingsJessica Ailani, MD, FAHS, FAAN; Paul G. Mathew, MD, DNBPAS, FAAN, FAHSView moreMultimediaCommunity Practice Connections™: Optimizing the Management of Tardive Dyskinesia—Addressing the Complexity of Care With Targeted TreatmentIlan Melnick, MD; Alejandro Alva, MD; Linda Trinh, DNP, PMHNP, FNP, MPHView moreMultimediaBurst CME™: Optimizing the Use of CGRP Targeted Agents for the Treatment of MigraineJessica Ailani, MD, FAHS, FAAN; Paul G. Mathew, MD, DNBPAS, FAAN, FAHSView moreMultimediaBurst CME™: The Patient Journey – Unmet Needs From Diagnosis Through Management of MigraineJessica Ailani, MD, FAHS, FAAN; Paul G. Mathew, MD, DNBPAS, FAAN, FAHSView moreMultimedia Evolving Perspectives in Alzheimer Disease : Reaching an Earlier Diagnosis, Understanding Neuroinflammation, and Exploring Therapeutic AdvancesAlireza Atri, MD, PhD; Erik S. Musiek, MD, PhD; Malú Gámez Tansey, PhDView moreVirtual EventExpert Illustrations & Commentaries™: Visualizing the Role of B Cells as Therapeutic Targets for Generalized Myasthenia GravisOctober 31, 2025View moreVideoCases and Conversations™: Applying Best Practices to Prevent Shingles in Your PracticePaul G. Auwaerter, MD, MBA; Paul P. Doghramji, MD, FAAFP; Aruna Subramanian, MDView moreVideoPatient, Provider, and Caregiver Connection™: Pediatric Myasthenia Gravis—Current Treatment and Emerging ConceptsJohn F. Brandsema, MD; Abigail N. Schwaede, MD; Samuel J. Mackenzie, MD, PhDView moreAudioMind Moments™: Optimizing Management for Patients with Generalized Myasthenia GravisJames F. Howard Jr, MDView moreVideoIdentifying and Treating CIDP in the Modern EraJeffrey A. Allen, MD; Karissa L. Gable, MDView moreVideoCases and Conversations™: Little Voices, Big Challenges – Comprehensive Care for Pediatric Spinal Muscular AtrophyJohn Brandsema, MD; Carla D. Zingariello, DOView moreVideoCases and Conversations™: Navigating the Complexities of Managing Myasthenia Gravis in Pediatric and Pregnant Patient PopulationsJohn Brandsema, MD; Neelam Goyal, MDView moreVideoA Breath of Strength: Managing Cancer Associated LEMS and Lung Cancer as OneEstelamari Rodriguez, MD, MPH; Millie Das, MD; Ruham Nasany, MDView moreVideoStriking the Right Nerve: Managing Cancer Associated LEMS in Lung Cancer PatientsAnne Chiang, MD, PhD; J. Douglas Miles, MD, PhD, FAAN; Suma Satti, MDView moreVideoPatient, Provider, and Caregiver Connection: Improving Diagnosis and Care for Adolescent Myasthenia Gravis Patients – A New FrontierAbigail N. Schwaede, MD; Emmanuelle (Noelle) Tiongson, MDView moreVideoA New Era in NMOSD Treatment: Optimizing Therapeutic Transitions and Reducing Patient BurdenShamik Bhattacharyya, MD, MS, FAAN; Mirla Avila, MD; Dean Wingerchuk, MDView moreAudioPER Podcast™: Maximizing the Multidisciplinary Care Outcomes of Patients with Amyotrophic Lateral Sclerosis (ALS)Richard Bedlack, MD, PhDView moreAudioPER Podcast™: Best Strategies for Approaching the Diagnosis of Amyotrophic Lateral Sclerosis (ALS)Terry Heiman-Patterson, MDView moreVideoPER Postgame™: Updates from ANNA in the Management of IgA NephropathyGerald Bernard Appel, MD; Ellie Kelepouris, MD, FACP, FAHAView moreVideoPatient, Provider, and Caregiver Connection: Turning a New Leaf in Acute Pain Management – How Recent Advancements Impact the Treatment ParadigmJeffrey Gudin, MD; Jeffrey Bettinger, PharmDView morePrevious slideNext slide Advertisement Advertisement Trending on NeurologyLive1Enhancing Gene Therapy Safety for Duchenne Through New Recommendations: Barry Byrne, MD, PhD2Expanding the Alzheimer Drug Development Pipeline 3FDA Hands Complete Response Letter to SL1009 for Pyruvate Dehydrogenase Complex Deficiency4Patient-Reported Study Identifies Common Symptoms and Timing During Migraine Prodrome 5Setting Realistic Expectations for Antiamyloid Therapeutics