Neuromodulators

What are neuromodulators? Neuromodulators are wrinkle-relaxing injections of botulinum toxin – commercially known as Botox Cosmetic, Dysport, Xeomin or Jeuveau – that are used to treat wrinkles, frown lines and crow’s feet. A minute amount of the neuromodulator is injected directly into the underlying muscle, causing it to relax and gradually smooth out the appearance of the overlying skin. The effects typically last about three months. Botox is the only neuromodulator FDA-approved to treat excessive sweating and crow’s feet – it’s actually been FDA-approved for the most treatment options. However, any neuromodulator can be used for these treatments. Their applications for these purposes is called “off-label” use, which simply means that they are being used in a way that was not part of their FDA clinical approval. A physician must inform you if any neuromodulator is being used “off-label.”