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Vepdegestrant extends progression-free survival in ER-positive, HER2-negative breast cancer

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1. In this randomized controlled trial, vepdegestrant achieved a longer progression-free survival than fulvestrant in patients with advanced ER-positive, HER2-negative breast cancer. 2. Vepdegestrant demonstrated an acceptable safety profile and was associated with a low rate of discontinuation due to adverse events. Evidence Rating Level: 1 (Excellent) Study Rundown: Cyclin-dependent kinase 4 and 6 (CDK4/6) […]

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